A successful
induction starts
with an open
cervix. And an
open cervix
can start with
CERVIDIL.
The more you
know, the better
you’ll feel
about choosing
CERVIDIL.
FDA-Approved CERVIDIL:
  • Is a small vaginal insert that works directly where it’s needed: on your cervix
  • Is easily removable using the retrieval string
  • Has medication that is out of your system minutes after the insert is removed
  • You may be able to move around 2 hours after it is inserted
CERVIDIL can help with the
first step of induction.

Before contractions begin, your cervix needs to relax and dilate (open) so labor can begin, a process called cervical ripening – a critical step before labor. If this doesn’t happen on its own, CERVIDIL can help. It’s important to speak to your Doctor or Midwife about CERVIDIL before delivery day so you are informed.

Why do I need CERVIDIL?

In order for labor to begin, your cervix needs to relax and dilate (open). When your body doesn’t do this on its own, CERVIDIL can help this process along.

How does CERVIDIL work?

Each CERVIDIL vaginal insert contains medicine called dinoprostone, which is similar to a natural prostaglandin found in your body. Dinoprostone signals your body to begin the process that helps your cervix gradually soften, thin, and dilate (open) as it would have done naturally.

How is CERVIDIL used?

CERVIDIL is only available at the hospital and is inserted by your healthcare professional. Once your cervix is properly dilated (opened), or after 12 hours, CERVIDIL can be easily removed by your Doctor or Midwife simply by pulling on the retrieval string (similar to how a tampon is removed). While CERVIDIL is working you may be able to get out of bed 2 hours after it is inserted.

Anxious, confused, even scared about labor induction?

Understanding how labor induction works and having an informed conversation with your Doctor or Midwife can help ease your uncertainty.

What does CERVIDIL look like?

CERVIDIL looks like a small, thin, flat tampon (around the size of a paperclip) with the medicine at one end,  and a retrieval string at the other end, for easy removal.

Ask your Doctor or Midwife about CERVIDIL

Download our Doctor Discussion & Patient Info Guide

The more you know, the better you’ll feel about choosing CERVIDIL

Please see important safety information and full prescribing information.

INDICATION

CERVIDIL® (dinoprostone, 10 mg) is a vaginal insert approved to start and/or continue the ripening of the cervix in pregnant women who are at or near the time of delivery and in whom there is a medical reason for inducing (bringing on) labor.

For the first two (2) hours following insertion, you should remain lying down. If you sit up or walk after the first two hours, you should be careful to ensure the insert remains in place. While CERVIDIL is inserted, your doctor will carefully monitor your progress and your baby’s well-being and will determine when the insert should be removed.

IMPORTANT SAFETY INFORMATION ABOUT CERVIDIL

CERVIDIL should only be inserted by a trained healthcare professional in a hospital setting appropriate for childbirth.

Who should NOT be given CERVIDIL?

You should NOT be given CERVIDIL if you have:

  • Experienced an allergic reaction to prostaglandins (certain hormone-like substances)
  • Experienced unexplained vaginal bleeding during your pregnancy
  • Already started receiving drugs to induce labor
  • Given birth six or more times in your lifetime

You should also NOT be given CERVIDIL if your doctor has determined that:

  • Your baby is in distress and needs to be delivered urgently
  • Your baby may be too large to fit through your birth canal (“cephalopelvic disproportion”)
  • Drugs used to induce labor are not appropriate for you or that prolonged contraction of your uterus may be harmful to you or your baby such as if you have had a previous cesarean section or major surgery on your uterus.

What are the most serious risks associated with the use of CERVIDIL?

The induction of labor has been associated with an increased risk of a disorder of abnormal clotting of the blood that results in excessive bleeding immediately after birth (“disseminated intravascular coagulation” or DIC). The risk is higher in women over age 30, those with complications during pregnancy, and those whose pregnancy has lasted longer than 40 weeks.

In rare cases, the use of CERVIDIL has been associated with an increased risk of a life-threatening event to the mother called “amniotic fluid embolism.” The cause of amniotic fluid embolism is not well understood but it is believed that some amniotic fluid or other substances can get into your bloodstream and start a severe reaction that can cause heart and lung collapse.

What should I discuss with my doctor before labor induction begins or CERVIDIL is given?

As you would throughout your pregnancy, be sure to tell your doctor about all prescription or over-the-counter medications you are taking. Before CERVIDIL is given, be sure you have told your doctor about all your current and past medical conditions, including:

  • If your water has broken
  • Any unexplained vaginal bleeding during pregnancy
  • All uterine surgeries, especially previous cesarean section
  • A history of contractions lasting more than 2 minutes
  • Glaucoma
  • Asthma, even if you had childhood asthma and have had no asthma attacks as an adult

What are the most common side effects of CERVIDIL?

The most common side effects associated with the administration of CERVIDIL are contractions occurring at a rate faster than normal (tachysystole) and signs that the baby is exhausted or in distress (uterine hyperstimulation). In clinical trials, these effects occurred alone or together in less than 1 in 20 women who were given CERVIDIL.

In clinical trials, fever, nausea, vomiting, diarrhea and abdominal pain were noted in less than 1 in 100 women who were given CERVIDIL.
This is not a complete list of possible side effects.

If you experience an adverse event please discuss it with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch/ or call 1-800-FDA-1088.

People depicted in images are models. Images used for illustrative purposes.

Please see full Prescribing Information

References: 1. CERVIDIL [package insert]. Parsippany, NJ: Ferring Pharmaceuticals Inc.  2. FDA Orange Book. https://www.accessdata.fda.gov/scripts/cder/ob/default.cfm. Accessed August 17, 2015.